CDMS mass spectometry
Advancing Progress In Charge Detection Mass Spectometry
RadMet manufactures custom pre-amplifiers for use in CDMS instruments. Our low-noise electronics measure charge levels on individual ions
with a sensitivity of less than +/- 100 electrons at room temperature.
The RadMet team pioneered the technique of charge detection mass spectrometry in the 1990s and used it to make the first direct mass measurement
of an intact virus. Interest is growing in the CDMS technique and RadMet is working on state-of-the-art electronics to support novel instrumentation
in this field.
RADMET CDMS pre-amplifiers
RADMET CDMS pre-amplifiers are state-of-the-art components for new generations of CDMS instruments.
RADMET Team publications
Fuerstenau, S.D. and Benner, W.H.: "Molecular Weight Determination
of Megadalton DNA Electrospray Ions using Charge Detection Time-of- Flight Mass Spectrometry," Rapid Communications in Mass Spectrometry, Vol. 15, pp. 1528-1538 (1995)
Fuerstenau, Stephen D., W. Henry Benner, John J. Thomas, Christophe Brugidou, Brian Bothner, and Gary Siuzdak: "Mass spectrometry of an. intact virus." Angewandte ChemieInternational Edition 40, no. 3 (2001): 541-544.
Partners: NASA, Lawrence Livermore Nat'l Security, ASTROBi
